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From genes to genomes: useful links

This is a list of additional resources for the From genes to genomes' theme and information sheets.

The Genome News Network (GNN)
An online magazine with a regularly updated list of all organisms whose genomes are sequenced. The site also has related news articles and links for published genome sequences. GNN is published by the J. Craig Venter Institute, in Rockville, Maryland.
http://www.genomenewsnetwork.org/

Consortium for the Barcode of Life (CBOL)
The Consortium for the Barcode of Life (CBOL) is an international initiative devoted to developing DNA barcoding as a global standard for the identification of biological species. This is their official website maintained by the National Museum of Natural History in the United States.
http://barcoding.si.edu/

FISH–BOL
A partner to CBOL, this website describes their activities to get DNA barcodes for all of the fish species around the world.
http://www.fishbol.org/

Books

Mapping the human genome
In his book Genome: The Autobiography of a Species in 23 Chapters, Matt Ridley examines what the mapping of the human genome may mean for the future. Published in 2000 by HarperCollins. ISBN: 0060932902.

Bacterial transformation

Bacterial cell structure
Get to know more about what’s inside a bacterial cell from CELLS alive!
http://www.cellsalive.com/cells/bactcell.htm

DNA, plasmids and bacterial transformation
Examples of plasmids that are used in the laboratory for bacterial transformation from Dr John Kimball at Harvard University.
http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/R/RecombinantDNA.html

Bacterial transformation
A step-by-step guide to doing a bacterial transformation in the lab from Plattsburgh the State University of New York.
http://faculty.plattsburgh.edu/donald.slish/Transformation.html

DNA cloning

DNA cloning in the laboratory
An informative presentation created by Linda McDonald, a New Zealand Science, Mathematics and Technology Teacher Fellow. The presentation is available in Powerpoint or pdf formats please go to ‘Gene cloning’ to access.
http://www.sbs.auckland.ac.nz/uoa/science/about/departments/sbs/student_information/....cfm

DNA cloning in action
An animation showing the key steps involved in DNA cloning, made by Max Animations.
http://www.maxanim.com/genetics/Cloning%20Gene/Cloning.Gene.htm

Making recombinant DNA in the classroom
A simple cut and paste paper activity to demonstrate DNA cloning, created by the Health and Bioscience teaching resource centre of the National Museum in Washington.
http://www.accessexcellence.org/RC/AB/WYW/wkbooks/SFTS/activity6.html

Microarrays/DNA chips

Anatomy of a comparative gene expression study
Detailed explanations about how microarrays are made and used, in very user-friendly language.
http://www.cs.wustl.edu/~jbuhler/research/array/

Microarrays: Chipping away at the mysteries of science and medicine
Another site with detailed information about microarrays, by the National Center for Biotechnology Information in the United States.
http://www.ncbi.nlm.nih.gov/About/primer/microarrays.html

DNA ligation

A closer look at ligation
A detailed explanation of ligation, including scientists proving that DNA fragments have been joined together by ligation. Developed by Colorado State University.
http://www.vivo.colostate.edu/hbooks/genetics/biotech/enzymes/ligation.html

DNA sequencing

The University of Michigan DNA Sequencing Core
An excellent explanation of the Sanger (di-deoxy) DNA sequencing method, with very clear diagrams.
http://seqcore.brcf.med.umich.edu/doc/educ/dnapr/sequencing.html

Information about the Human Genome Project
Find out what the Human Genome Project was, whose genome was sequenced, how it was done and what happens now that the human genome has been completely sequenced.
http://www.ornl.gov/sci/techresources/Human_Genome/faq/seqfacts.shtml

Ethics and the Human Genome Project
Contains a comprehensive list of the ethical, legal and social issues that need to be considered as our knowledge about DNA and genes grows.
http://www.ornl.gov/sci/techresources/Human_Genome/elsi/elsi.shtml

An animation
Explore a stretch of DNA code. Look for genes and regions of genetic variation. Requires shockwave.
http://www.pbs.org/wgbh/nova/genome/explore.html

Gel electrophoresis

Gel electrophoresis (Colorado State University Biotechnology Index)
This site provides an excellent explanation of gel electrophoresis and has a link to a very good interactive activity for senior biology students.
http://arbl.cvmbs.colostate.edu/hbooks/genetics/biotech/gels/agardna.html

Restriction enzymes

Examples of restriction enzymes and their recognition sites
Information about restriction enzymes created specifically for high schools by the University of Otago.
http://highschoolbiology.otago.ac.nz/molbiol.html

A closer look at restriction enzymes
A detailed explanation of restriction enzyme activity, including specific examples, developed by Colorado State University. http://www.vivo.colostate.edu/hbooks/genetics/biotech/enzymes/index.html

DNA barcoding

Barcode of life
Homepage for the barcode of life website with information on the project.
http://www.barcoding.si.edu/

The barcode blog
Articles and viewpoints relating to DNA barcoding.
http://cybercampus.rockefeller.edu/barcode/blog/

Sponge barcoding
Information about sponge species and their barcode project.
http://www.spongebarcoding.org/

Bird barcoding
Information about bird species and their barcode project.
http://barcoding.si.edu/AllBirds.htm

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